3-Butoxy-7-ethoxy-4,6-difluoro-dibenzothiophene

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-12-20 to 2019-01-08

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

Deviations:

no

GLP compliance:

no

Type of method:

sieving

Type of particle tested:

primary particle

Type of distribution:

mass based distribution

Percentile:

D10

Mean:

500 µm

St. dev.:

0

Key result

Percentile:

D50

Mean:

1 250 µm

St. dev.:

0

Percentile:

D90

Mean:

2 350 µm

St. dev.:

0

The particle size distribution was determined by dry sieving as only approximately 50 % of the test item passed a 1000 µm sieve and thus laser diffraction was therefore not applicable. 235.89 g of the test item were placed on the top sieve. After closing the sieve stack and placing it into the sieving machine sieving was performed for 4 min with an amplitude of 1.0 mm.

 

Mesh size um	Range of particle size µm	Fraction g	Total g	Fraction %	Total %
2500	> 2500	13.30	13.30	5.64	5.64
1600	1600-2500	62.80	76.10	26.62	32.26
1250	1250-1600	39.95	116.05	16.94	49.20
1000	1000-1250	30.85	146.90	13.08	62.27
800	800-1000	22.66	169.56	9.61	71.88
630	630 - 800	19.17	188.73	8.13	80.01
500	500 - 630	25.33	214.06	10.74	90.75
300	300 - 500	17.78	231.84	7.54	98.28
200	200 - 300	3.51	235.35	1.49	99.77
150	150-200	0.49	235.84	0.21	99.98
Receiver pan	0-150	0.13	235.97	0.06	100.03*

*The slight difference was most likely caused by minor balance deviations and had no significant influence on the results.

 

Conclusions:

The median particle sizes D10, D50 and D90 were determined to be 500 µm, 1250 µm and 2350 µm, respectively.

Executive summary:

A study was conducted according to OECD TG 110 determine the particle size distribution of the test item. The particle size distribution was determined by dry sieving as only approximately 50 % of the test item passed a 1000 µm sieve and thus laser diffraction was therefore not applicable. 235.89 g of the test item were placed on the top sieve. After closing the sieve stack and placing it into the sieving machine sieving was performed for 4 min with amplitude of 1.0 mm. The median particle sizes D10, D50 and D90 were determined to be 500 µm, 1250 µm and 2350 µm, respectively.

Description of key information

The median particle sizes D10, D50 and D90 were determined to be 261 µm, 605 µm and 1270 µm, respectively.

Additional information

A study was conducted according to OECD TG 110 determine the particle size distribution of the test item (reference 4.5 -1). The particle size distribution was determined by dry sieving as only approximately 50 % of the test item passed a 1000 µm sieve and thus laser diffraction was therefore not applicable. 235.89 g of the test item were placed on the top sieve. After closing the sieve stack and placing it into the sieving machine sieving was performed for 4 min with amplitude of 1.0 mm. The median particle sizes D10, D50 and D90 were determined to be 500 µm, 1250 µm and 2350 µm, respectively.