Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 947-816-1 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Data source
Reference
- Reference Type:
- publication
- Title:
- Hypoglycaemic effect of Trigonella foenum graecum and Lupinus termis (leguminosae) seeds and their major alkaloids in alloxan-diabetic and normal rats.
- Author:
- Mishkinsky
- Year:
- 1 974
- Bibliographic source:
- Arch Int Pharmacodyn Ther. 1974 Jul;210(1):27-37.
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- pre guideline time, equvalent or similar to later OECD 401
- GLP compliance:
- no
- Test type:
- up-and-down procedure
Test material
- Reference substance name:
- 1-methylpyridinio-3-carboxylate
- EC Number:
- 208-620-5
- EC Name:
- 1-methylpyridinio-3-carboxylate
- Cas Number:
- 535-83-1
- Molecular formula:
- C7H7NO2
- IUPAC Name:
- 1-Methylpyridinio-3-carboxylate
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 5 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- LD50 > 5000 mg/kg bw
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