Registration Dossier
Registration Dossier
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EC number: 231-324-2 | CAS number: 7492-67-3
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1973
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
- Report date:
- 1973
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- [(3,7-dimethyl-6-octenyl)oxy]acetaldehyde
- EC Number:
- 231-324-2
- EC Name:
- [(3,7-dimethyl-6-octenyl)oxy]acetaldehyde
- Cas Number:
- 7492-67-3
- Molecular formula:
- C12H22O2
- IUPAC Name:
- 2-[(3,7-dimethyloct-6-en-1-yl)oxy]acetaldehyde
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Doses:
- 5 g/kg body weight dose
- No. of animals per sex per dose:
- Animals dose, the number per sex was not specified.
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No mortality.
- Clinical signs:
- other: No clinical signs observed.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Based on the study, the acute dermal LD50 was greater than 5 g/kg bw.
- Executive summary:
A acute dermal LD50 study was conducted in which 10 rabbits received a dermal application of 5 g/kg of the test material. The animals were observed for mortality and/or systemic effects. No clinical signs were observed in the rabbits and the LD50 was reported as greater than 5 mg/kg body weight.
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