Reaction mass of 1-(3,3-dimethylcyclohexyl)ethyl acetate and 2,6,6-trimethylcycloheptanol acetate

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2019-03-15 to 2019-03-18

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

>= 228 - <= 230 °C

Atm. press.:

1 013.25 hPa

Decomposition:

no

Results of the DSC-measurements

No.	Sample weight/ mg	Onset of Effect/ °C	Range of effect rc	Weight loss/ mg	Atmospheric pressure / hPa
PN17469	11.95	227.60	170 - 240 (endo)	11.95	992.9
PN17477	11.44	229.27	160 - 240 (endo)	1143	1006.1

 

During the subsequent heating phase, an endothermic effect was observed in the temperature range of 160 – 240 °C, which can be assigned to the boiling of the test item. For the correction of the boiling temperature to standard pressure the test item was assigned to chemical group 2 (e.g. Hydrocarbons/Esters). According to appendix 8.2 a correction valueφ= 5.0 was used for the temperature of 220 – 230 °C. The lowest measured onset temperature is corrected to the standard pressure to be 228.48 °C and the highest onset temperature to be 229.58 °C. As the corrected onset temperatures in both tests deviate by more than 0.5 K from their mean value of 229.03 °C, the test item has a boiling range of 228 °C – 230 °C. No further thermal effects were observed up to the maximum test temperature of 500 °C.

Conclusions:

The boiling range of the test item was determined to from 228 to 230 °C.

Executive summary:

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 11 -12 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. At ambient conditions, the test item is a liquid. The temperature was increased up to 500 °C at a constant heating rate of 10 K/min. During the heating phase, an endothermic effect was observed in the temperature range of 160 – 240 °C, which was assigned to the boiling of the test item. The boiling point was corrected to normal pressure (1013.25 hPa) according to the Equation, table and figures of H.N. Hass and R.F. Newton. The lowest measured onset temperature is corrected to the standard pressure to be 228.48 °C and the highest onset temperature to be 229.58 °C. As the corrected onset temperatures in both tests deviate by more than 0.5 K from their mean value of 229.03 °C, the test item has a boiling range of 228 °C – 230 °C. No further thermal effects were observed up to the maximum test temperature of 500 °C.

Description of key information

The boiling range of the test item was determined to from  228 to 230 °C.

Additional information

A study was conducted according to OECD test guideline 103, Regulation (EC) No 440/2008 method A.2 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 11 -12 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. At ambient conditions, the test item is a liquid. The temperature was increased up to 500 °C at a constant heating rate of 10 K/min. During the heating phase, an endothermic effect was observed in the temperature range of 160 – 240 °C, which was assigned to the boiling of the test item. The boiling point was corrected to normal pressure (1013.25 hPa) according to the Equation, table and figures of H.N. Hass and R.F. Newton. The lowest measured onset temperature is corrected to the standard pressure to be 228.48 °C and the highest onset temperature to be 229.58 °C. As the corrected onset temperatures in both tests deviate by more than 0.5 K from their mean value of 229.03 °C, the test item has a boiling range of 228 °C – 230 °C. No further thermal effects were observed up to the maximum test temperature of 500 °C.