Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07 Jan 2019 - 14 Feb 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
- Appearance: Off-white powder
- Storage condition of test material: In refrigerator protected from light
Specific details on test material used for the study:
Decomposition temp.: 250°C

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
<= 0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
<= 0 Pa

Any other information on results incl. tables

Table: Results of the vapour pressure isothermal TGA analysis (substance):

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

logνT

logPT

PT
[Pa]

100

0.827012

9.87 x 10-5

-4.01

-0.01

0.97

 

0.751190

8.97 x 10-5

-4.05

-0.06

0.86

110

1.58243

1.89 x 10-4

-3.72

0.35

2.2

 

1.48332

1.77 x 10-4

-3.75

0.31

2.0

120

3.05497

3.65 x 10-4

-3.44

0.71

5.1

 

2.93233

3.50 x 10-4

-3.46

0.68

4.8

130

5.74671

6.86 x 10-4

-3.16

1.05

11

 

5.59520

6.68 x 10-4

-3.18

1.04

11

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C and 25°C was determined to be ≤ 9.3E-5 Pa and ≤ 1.9E-4 Pa, resp.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study based on EC A.4, OECD 104 and OPPTS 830.7950. Validation of the method was performed using a set of five reference substances.

The vapour pressure regression curve (log PT as function of 1/T; with T in K) of the substance was constructed from weight losses measured at 100°C, 110°C, 120°C and 130°C.

The vapour pressure of the substance at 20°C and 25°C was calculated from the vapour pressure curve.

Since the weight losses of the test item were obtained with a temperature program of above the melting temperature of the test item, the vapour pressure of the test item could be slightly overestimated. The vapour pressure of the substance at 20°C and 25°C was therefore reported as ≤ 9.3E-5 Pa and ≤ 1.9E-4 Pa, resp.