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Endpoint summary
Administrative data
Description of key information
For substituted amino acid (2) solution (CAS no.: CBI), which is an industrial intermediate substance, two aquatic ecotoxicity test results are available and information on the inhibition of micro-organisms presenten in activated sludge and in river water.
Based on the results of a short-term aquatic toxicity study, performed according to OECD 201 and GLP principles, Substituted amino acid (2) solution inhibited growth of Pseudokirchneriella subcapitata at analytically confirmed nominal concentrations of 18 mg/L and higher. Based on biological relevance, the 72 h-NOErC was determined to be 100 mg/L. The 72 h-ErC50 and 72h-ErC10 and NOEC were determined to be >100 mg/L.
Based on the results of a short-term aquatic toxicity study, performed according to OECD 202 and GLP principles, Substituted amino acid (2) solution showed no toxicity towards Daphnia magna in a 48 hour exposure period when tested up to a limit concentration of 100 mg/L. Therefore, the 48h-EC50 was determined to exceed an analytically confirmed nominal concentration of 100 mg/L.
The toxicity of substituted amino acid (2) solution FC-C 13587 to activated sludge was determined according to OECD 209 under GLP conditions at a contact time of 3 hours, using various concentrations of the test substance. The inhibitory effect of substituted amino acid (2) solution FC-C 13587 at a particular concentration is expressed as a percentage of the two controls. From the results EC values were calculated. The EC10 of substituted amino acid (2) solution FC-C 13587 for activated sludge after 3 hours contact time is 164.3 mg a.i./L with 95% confidence limits of 76.7 and 815.4 mg/L. The EC20, EC50 and EC80 of substituted amino acid (2) solution FC-C 13587 for activated sludge could not be determined. Substituted amino acid (2) solution FC-C 13587 is therefore considered not harmful to activated sludge.
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