Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 234-766-4 | CAS number: 12032-30-3
Skin sensitisation
Some information in this page has been claimed confidential.
Administrative data
- Endpoint:
- skin sensitisation: in vitro
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- other: Disseminated dossier
- Title:
- REACh registration of Calcium titanium trioxide
- Author:
- Yordas GmbH
- Year:
- 2 018
- Bibliographic source:
- ECHA
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Bibliographic review
- Type of study:
- not specified
- Justification for non-LLNA method:
- Bibliographic review
Test material
- Reference substance name:
- Calcium titanium trioxide
- EC Number:
- 234-988-1
- EC Name:
- Calcium titanium trioxide
- Cas Number:
- 12049-50-2
- Molecular formula:
- Ca.O3Ti
- IUPAC Name:
- Calcium titanium trioxide
- Reference substance name:
- Titanium dioxide
- EC Number:
- 236-675-5
- EC Name:
- Titanium dioxide
- Cas Number:
- 13463-67-7
- Molecular formula:
- O2Ti
- IUPAC Name:
- dioxotitanium
- Reference substance name:
- Silicon dioxide
- EC Number:
- 231-545-4
- EC Name:
- Silicon dioxide
- Cas Number:
- 7631-86-9
- Molecular formula:
- O2Si
- IUPAC Name:
- dioxosilane
- Reference substance name:
- Magnesium oxide
- EC Number:
- 215-171-9
- EC Name:
- Magnesium oxide
- Cas Number:
- 1309-48-4
- Molecular formula:
- MgO
- IUPAC Name:
- magnesium oxygen(-2) anion
- Reference substance name:
- Diniobium pentaoxide
- EC Number:
- 215-213-6
- EC Name:
- Diniobium pentaoxide
- Cas Number:
- 1313-96-8
- Molecular formula:
- Nb2O5
- IUPAC Name:
- diniobium pentoxide
- Test material form:
- solid: nanoform, surface-treated
Constituent 1
impurity 1
impurity 2
impurity 3
impurity 4
impurity 5
Results and discussion
In vitro / in chemico
Results
- Key result
- Remarks on result:
- no indication of skin sensitisation
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- An assessment was performed based on available information on the substance and experimental data on a suitable analogue. It concluded that Calcium Titanium Trioxide is not expected to induce skin sensitisation.
Based on read-across from Calcium titanium Trioxide, Magnesium titanate is not skin sensitive.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
