2-(4-Bromphenyl)-5-butyl-1,3-dioxane, trans-

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-01-18 to 2018-01-19

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

no

Type of method:

effusion method: Knudsen cell

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

0 Pa

Key result

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

0.001 Pa

Test no.:

#3

Temp.:

50 °C

Vapour pressure:

0.025 Pa

The vapour pressure was measured in the temperature range of 70 °C to 105 °C. The measured vapour pressures at the corresponding temperatures are listed in Table 1. After the measurement a mass loss of 100 % (w/w) was determined.

 

Table 1: Measured vapour pressures and corresponding temperatures

Temperature /°C	Vapour pressure / hPa
70	2.8 x 10-3
75	5.6 x 10-3
80	9.5 x 10-6
85	1.5 x 10-2
95	n.e.
105	n.e.

n.e.: not evaluable

 

As the test cell was empty after the measurement at 85 °C, no evaluable data could be obtained at 95 °C and 105 °C.

Figure 1 on page 7 gives the vapour pressure (logarithmic scale) as a function of the inverse
The values for 20, 25 and 50 °C are calculated, using the Antoine constants A, B and C.

 

The following vapour pressure values for the test item were extrapolated from the experimental data (vapour pressure balance):

 

- at 20 °C : 3.4E-4Pa

- at 25 °C : 7.3E-4Pa

- at 50 °C : 2.5E-2Pa

Conclusions:

The vapour pressure at 20, 25 and 50 °C was determined to be 0.00034, 0.00073 and 0.0025 Pa respectively.

Executive summary:

A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item. The vapour pressure of the test item was determined at different temperatures (70 - 105 °C) using the effusion method (weight loss). The vapour pressure was calculated using the linear regression equation of the Log P versus 1/T function. The values for 20, 25 and 50 °C were calculated using the Antoine equation. The vapour pressure was determined to be 0.00034, 0.00073 and 0.0025 Pa respectively.

Description of key information

The vapour pressure at 20, 25 and 50 °C was determined to be 0.00034, 0.00073 and 0.0025 Pa respectively (reference 4.6 -1).

Key value for chemical safety assessment

Vapour pressure:

0.001 Pa

at the temperature of:

25 °C

Additional information

A study was conducted according to OECD TG 104, Regulation (EC) No 440/2008 method A.4 and OPPTS 830.7950 to determine the vapour pressure of the test item (reference 4.6 -1). The vapour pressure of the test item was determined at different temperatures (70 - 105 °C) using the effusion method (weight loss). The vapour pressure was calculated using the linear regression equation of the Log P versus 1/T function. The values for 20, 25 and 50 °C were calculated using the Antoine equation. The vapour pressurewas determined to be 0.00034, 0.00073 and 0.0025 Pa respectively.