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EC number: -
CAS number: -
Upsalite is not considered to be irritating to the skin and main
constituents are not considered to be irritating to the eyes.
Table 1 Summary of opacity, permeability and in vitro scores
MeanIn vitroIrritation Score1,2
1. Calculated using the negative control mean opacity an mean
2. In vitro irritancy score (IVIS)= mean opacity + (15X mean OD490value).
Table 2. Opacity score
Opacity before treatment
Opacity after treatment
Negative control corrected final opacity
Table 3. Permeability score (corrected)
Table 4. In vitro irritancy score
Negative control corrected final OD490
In vitro irritancy score
In vitro irritancy score (IVIS) = mean opacity + (15 x mean OD490value)
Screening for the eye irritancy potential of Magnesium hydroxide using
the BCOP test. The study procedures were based on OECD guidelines.
Magnesium hydroxide did not induce ocular irritation through both
endpoints, resulting in a meanin vitroirritancy score of 5.1
after 240 minutes of treatment. Since this score is below 55.1 after 240
minutes treatment, Magnesium hydroxide is not classified as an irritant
in the BCOP test.
In thein vitro skin irritation (upsalite )and the in vivo eye
irritation studies, magnesium carbonate and magnesium hydroxide were
non-irritant and therefore requires no classification under the
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