α-d-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-d-glucopyranuronosyl-, dipotassium salt

Guidance on Safe Use

First-aid measures

First-aid measures general : If you feel unwell, seek medical advice (show the label where possible).

First-aid measures after inhalation : In the event of inhalation of dust, remove the person to fresh air, keep warm and at rest.

Consult a doctor if respiratory symptoms appear or persist.

First-aid measures after skin contact : Wash with plenty of water/…. Seek medical advice if an irritation appears.

First-aid measures after eye contact : Rinse carefully with plenty of water with the eyelids held wide open. Seek an eye specialist’s

advice if an irritation appears.

First-aid measures after ingestion : Do not induce vomiting without seeking medical advice. If the person is conscious, rinse mouth

with water. Call a doctor.

Fire-fighting measures

-Extinguishing media

Suitable extinguishing media : Water spray with additives, chemical powder, chemical foam, carbon dioxide extinguisher.

Unsuitable extinguishing media : Solid water jet.

Avoid high pressure media which could cause the formation of a potentially explosible dust-air mixture.

-Special hazards arising from the substance or mixture

Explosion hazard : Suspension of the dust in the air could produce an explosive atmosphere.

Hazardous decomposition products in the event of fire : In case of fire or combustion, the product may release dangerous decomposition products such as carbon monoxide and dioxide.

- Advice for firefighters

Protection in the event of a fire : Do not enter fire area without proper protective equipment, including respiratory protection.

Other information : Packaging exposed to heat or open flames should be cooled with a fine water spray. Prevent fire-fighting water from entering drains.

Accidental release measures

-Personal precautions, protective equipment and emergency procedures

For non-emergency personnel

Protective equipment : Personal protection : see section 8.

Emergency procedures : Avoid contact with eyes and skin. Avoid breathing dust.

Measures in case of dust release : Do not allow the material to become suspended in the air.

For emergency responders

Protective equipment : Personal protection : see section 8.

Emergency procedures : Avoid contact with eyes and skin. Avoid breathing dust.

-Environmental precautions

Avoid release into natural bodies of water, waste water or the soil. Contain the leak or spill from spreading if it can be done without any danger. Do not discharge to surface water or to sewers. Inform local authorities if significant leaks cannot be contained.

-Methods and material for containment and cleaning up

For containment : Suitable advice concerning the containment of a spill; the following containment methods can be envisioned:

- To limit the production of dust or vapour: cover the product with absorbent granules (inert, non

flammable and non combustible).

- In case of large spills: install a protective enclosure, cover the sewers.

Collect the absorbent/product mixture and put it in compatible packaging for subsequent disposal in accordance with the regulations in force.

In case of a large spill, inform the competent authorities if the situation cannot be rapidly and effectively controlled.

The absorbent/product mixture shall be handled with the same precautions as the product itself.

Methods for cleaning up : To clean: wash the contaminated area making sure not to contaminate the natural environment.

During the cleaning operations, continue to abide by the handling precautions.

-Reference to other sections

For information on handling, see section 7. For information on personal protective equipment, see section 8. For information on disposal, see section 13.

Handling and storage

-Precautions for safe handling

Additional hazards when processed : Ensure adequate ventilation.

Precautions for safe handling : Avoid contact with skin and eyes. Avoid breathing dust. Avoid raising powdered materials into airborne dust.

Hygiene measures : Use personal protective equipment (appropriate gloves, splash goggles, suitable work clothing) in accordance with industrial hygiene best practices (see section 8).

-Conditions for safe storage, including any incompatibilities

Storage conditions : - Conditions for storing the product in safety: Store in its original packaging, closed and in a dry and well ventilated area. Avoid extreme temperatures (heat and cold).

- For more details on storage conditions to ensure product quality: Refer to the data sheet.

Combustible dust. Make sure that the storage conditions are appropriate for this risk and for the applicable regulations covering the prevention of explosive atmospheres.

Incompatible products : Oxidising agent. Strong acids. Strong bases.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

Not regulated for transport

Shipping

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

Not regulated for transport

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

Not regulated for transport

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

Not regulated for transport

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Exposure controls

Appropriate engineering controls : Use only in well ventilated areas.

Hand protection : Due to the many possible conditions of exposure, the user should consider the actual period of use of a chemical protection glove to be significantly shorter than the period prior to

permeation. It is essential to comply with the manufacturer's instructions for use, in particular concerning minimum thickness and minimum period prior to permeation. This information in no

way replaces the compliance tests conducted by the final user. The protection provided by the glove depends on the conditions in which the substance/mixture is used. At the very least use

chemical-resistant, leak-proof gloves (in accordance with standard EN 374). The use of this product means that the type of material and thickness of the gloves as well as the time taken to

break down the material used to make the gloves cannot be decided until an in-depth study of the workstation has taken place, leading to a clear definition of the conditions of use and the

most accurate possible evaluation. The gloves should therefore be chosen with the advice of the personal protective equipment manufacturer. In case of repeated or prolonged contact we

suggest that you wear neoprene or nitrile rubber gloves (according to standard EN 374).

Eye protection : We suggest that you wear goggles if a large amount of dust is spread. Goggles with lateral protection (according to standard EN 166).

Skin and body protection : Skin protection appropriate to the conditions of use should be provided. Wear suitable protective clothing.

Respiratory protection : In the event of insufficient ventilation, wear suitable respiratory equipment. Dust/aerosol filter, type P3 (in accordance with standard EN 143).

Environmental exposure controls : Avoid release into natural bodies of water, waste water or the soil.

Consumer exposure controls : Take off contaminated clothing and wash before reuse. Wash hands after working with the product.

Other information : Do not eat, drink or smoke during use.

Stability and reactivity

-Reactivity

Reactivity relating to the substances, containers and contaminants to which the substance or mixture may be exposed during their transport, storage and use : No data available.

-Chemical stability

The product is stable in normal conditions of use. Stability of the substance or mixture under normal and predictable storage and handling room conditions in terms of temperature and pressure : Chemically stable under standard room conditions (room temperature).

-Possibility of hazardous reactions

Reaction or polymerisation of the substance or mixture releasing excessive heat or pressure or generating other dangerous conditions : This product will not polymerise by releasing excessive heat or pressure or by generating other dangerous conditions. (See section 10.1 for reactivity which can generate risks by taking into account the substances, containers and contaminants to which the substance or mixture may be exposed

during their transport, storage and use.).

-Conditions to avoid

Listing of conditions such as temperature, pressure, light, shocks, electrostatic discharges, vibrations or other physical stresses which may lead to a dangerous situation : According to our knowledge, temperature, pressure, light, shocks, etc. do not lead to a dangerous situation. Keep away from open flames, hot surfaces and ignition sources. Do not allow the dust to become suspended in the air; it could produce an explosive atmosphere.

-Incompatible materials

Families of substances or mixtures, or specific substances, such as water, air, acids, bases, oxidisng agents, with which the substance or mixture

may react by generating a dangerous situation : Strong oxidising agents, strong acids and strong bases.

-Hazardous decomposition products

Known dangerous decomposition products and products which may be reasonably predictable as such following use, storage, pouring and heating :

This product does not decompose under normal conditions. Decomposition products in case of fire : consult section 5.2.

Disposal considerations

-Waste treatment methods

Waste treatment methods : Dispose of in accordance with the local/national safety regulations in force.

Product/Packaging disposal recommendations : They must be disposed of in accordance with the local regulations in force.

Additional information : It is recommended to avoid or reduce waste production as much as possible.

The disposal of this product, solutions and by-products shall comply with the legal requirements for environmental protection and waste disposal and the requirements of all local authorities at all times.

A licensed waste disposal contractor will be in charge of the disposal of surplus and nonrecyclable products. Do not evacuate untreated waste into the sewers.

Only dispose of this product and its container by taking all standard precautions. Handle noncleaned and non-rinsed containers with care. Empty containers or liners may retain product residues. Avoid dispersing spilled materials, as well as their leakage, and any contact with the soil, waterways, drains and sewers.