Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Manufacture, use & exposure

Manufacture

Manufacture

Registration/ Notification status for the use:
use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Manufacture name:
Intermediate
Reference
Name:
tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate
Type of composition:
legal entity composition of the substance
State / form:
solid: bulk
ca. 98 - < 100 % (w/w)
Reference substance:
tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate
Reference substance:
tert-Butyl 4-({6-[7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino}pyridin-3-yl)piperazine-1-carboxylate
This impurity is considered relevant for the classification and labelling of the substance
Contributing activity / technique for the environment
Name of activity / technique:
The substance is used as intermediate
Environmental release category (ERC):
ERC1: Manufacture of the substance
Contributing activity / technique for workersopen allclose all
Name of activity / technique:
Reaction
Process category (PROC):
PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
Name of activity / technique:
Charging / Discharging
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Related assessment:
use assessed in an own CSR

Contributing scenario for the environment (related to workers activities)

Conditions of use for the environment

Conditions and measures related to Biological Sewage Treatment Plant

Biological Sewage Treatment Plant (STP):
no

Conditions and measures related to external treatment of waste (including article waste)

Particular considerations on the waste treatment operations:
no

Other conditions affecting environmental exposure

Place of use:
indoor

Releases to waste and the environment

Release to external waste

ContribScenWorkersRepopen allclose all

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with high dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Other conditions affecting workers exposure

Place of use:
indoor

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Physical form of the used product:
solid (material with high dustiness)

Amounts used (or contained in articles), frequency and duration of use/exposure

Other conditions affecting workers exposure

Place of use:
indoor