Registration Dossier
Registration Dossier
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EC number: 246-148-1 | CAS number: 24308-84-7
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- Testing by dermal route does not need to be conducted because:
- the substance does not meet the criteria for classification as acute toxicity or STOT SE by the oral route and
- no systemic effects have been observed in in vivo studies with dermal exposure (e.g. skin irritation, skin sensitisation) or, in the absence of an in vivo study by the oral route, no systemic effects after dermal exposure are predicted on the basis of non-testing approaches (e.g. read across, QSAR studies).
Test substance was found to be non toxic by oral route in an in vivo study in rats (OECD 423). Moreover, in an in vitro skin irritation assay (OECD 439), no signs of toxicity were seen, as average tissue viability was found to be 97 - 100 % of negative control value.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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