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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
no

Test material

1
Reference substance name:
Silybum marianum extract
Molecular formula:
Not applicable
IUPAC Name:
Silybum marianum extract
Test material form:
liquid
Details on test material:
The test matérial contains 0.5% of tocophérol for stability

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Water media type:
not specified
Limit test:
no
Total exposure duration:
72 h

Test conditions

Hardness:
Not specified
Test temperature:
Not specified
pH:
Not specified
Dissolved oxygen:
Not specified
Salinity:
Not specified
Conductivity:
Not specified
Nominal and measured concentrations:
Not specified
Reference substance (positive control):
yes
Remarks:
Potassium dichromate

Results and discussion

Effect concentrations
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
ca. 21.73 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
not specified
Basis for effect:
cell number
Details on results:
95% confidence interval : 21.25 - 22.42 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The result obtained for EC50 is 21.73 mg / L.
Executive summary:

The objective of this work is the determination of acute toxicity of LIPOLAMI milk thistle ER on aquatic algae according OECD 201 method.

The result obtained for EC50 is 21.73 mg / L.