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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
According to Article 13 of Regulation (EC) No. 1907/2006"General Requirements for Generation of Information on Intrinsic Properties of substances", Information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met.
Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”.
Since the group concept is applied to the members of the Polyol esters group, data will be generated from a representative category member to avoid unnecessary animal testing. Additionally, once the group concept is applied, substances will be classified and labelled on this basis.
Degradation
Biodegradation: readily biodegradable (96 % after 28 d; EU Method C.4-C)
Bioaccumulation
Expert statement: Bioaccumulation is assumed to be low.
Aquatic acute toxicity
For fish: no effects up to the limit of water solubility
For aquatic invertebrates: no effects up to the limit of water
solubility (read across)
For algae/aquatic plants: no effects up to the limit of water solubility
(read across)
Aquatic chronic toxicity
For fish: no data available
For aquatic invertebrates: no effects up to the limit of water
solubility (read across)
NOTE: Although chronic toxicity data is available for members within the polyol esters category in accordance to Regulation (EC) No 1907/2006, Annex IX 9.1 Aquatic toxicity, we plan a read across to proposed tests on long term toxicity to invertebrates for the PE esters CAS 15834-04-5, EC # 270-290-3, formerly known was CAS 68424-30-6 (C5, C7, C9 iso) and CAS 68424-31-7. CAS 15834-04-5 has the shortest chain length (C5) of PE esters, it is a mono-constituent and often is a constituent with many of the other polyol esters. Due to its smaller molecular size it is expected to have the highest bioavailability. EC # 270-290-3, formerly known was CAS 68424-30-6 (C5, C7, C9 iso) was chosen on the basis of its isononanoic acid content to evaluate possible adverse effects. CAS 68424-31-7 (C5, C7, C8 , C9 and C10) is a highly complex UVCB, with varying chain lengths and combinations of structures. CAS 85049-33-8 was selected to represent the medium chain length of the category C8, C10 and C12, which is of concern here. As soon as this data is available the hazard and chemical safety assessment will be updated.
For algae/aquatic plant: 72 h, NOELR (Desmodesmus subspicatus): no effects up to the limit of water solubility (read across)
CLP:
Tetra-esterification products of C5, C7, C8, C9, C10
fatty acids with pentaerythritol (CAS 68424-31-7) is expected to be
readily biodegradable and has a low potential to bioaccumulate. The
substance is considered to be not acutely toxic to fish, aquatic
invertebrates or algae since not toxic effects were observed up to the
limit of water solubility (< 1 mg/L). Data on chronic toxicity indicate
no toxicological effects up to the limit of water solubility.
Tetra-estrification products of C5, C7, C8, C9, C10 fatty acids with
pentaerythritol (CAS 68424-31-7) does not need to be classified and
labelled as environmental hazardous according to the Regulation (EC) No
1272/2008 and the Regulation (EU) No 286/2011 (2nd ATP).
DSD:
Tetra-estrification products of C5, C7, C8, C9, C10
fatty acids with pentaerythritol (CAS 68424-31-7) is expected to be
readily biodegradable and has a low potential to bioaccumulate. The
substance is poorly soluble in water and no effects occurred up to the
water solubility limit (< 1 mg/L) in acute tests for fish, algae and
aquatic invertebrates. Tetra-esterification products of C5, C7, C8, C9,
C10 fatty acids with pentaerythritol (CAS 68424-31-7) does not need to
be classified and labelled as environmental hazardous according to
Directive 67/548/EEC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.