Registration Dossier
Registration Dossier
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EC number: 253-897-8 | CAS number: 38353-09-2
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- The determination was carried out by differential scanning calorimetry, using a procedure designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- Pyrimidine-2-ol hydrochloride
- EC Number:
- 253-897-8
- EC Name:
- Pyrimidine-2-ol hydrochloride
- Cas Number:
- 38353-09-2
- Molecular formula:
- C4H4N2O.ClH
- IUPAC Name:
- pyrimidin-2-ol hydrochloride
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Melting / freezing point
- Key result
- Decomposition:
- yes
- Decomp. temp.:
- ca. 166 °C
- Remarks on result:
- other: The absence of any phase transition (i.e. melting) prior to decomposition was confirmed by a visual metal-block apparatus evaluation. On heating, the test item gradually discolored, before collapsing into a black solid. No liquid phase was observed at any
Applicant's summary and conclusion
- Conclusions:
- The test item was determined to decompose, without melting, from approximately 166 °C (439 K). Decomposition was observed in both air and nitrogen atmospheres.
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