Registration Dossier
Registration Dossier
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EC number: 939-579-8 | CAS number: -
Stability in organic solvents and identity of relevant degradation products
Administrative data
Link to relevant study record(s)
Description of key information
Stable in 2 -propanol at 50°C over a period of 120 hours
No stable test design could be established with n-hexane. Test item losses of 19-55% at 50°C over a period of 120 hours were observed. However, no chemical explanation could be given for the test item losses and the changes in study design (concentration, test container and sample preparation) lead to changes in the test item recovery. It was concluded that irreversible adsorption of the test item to the test container walls might be the most probable reason for test item elimination.
Additional information
The test item was found to be stable in 2 -propanol at 50°C over a period of 120 hours, because no significant degradation (<10%) of the test item in 2 -propanol was observed at test conditions.
For n-hexane two 120 hours studies, several non GLP experimental screening and a 120 hours non-GLP study were performed, but no stable test design could be established. Indeed, as result of these studies varying losses of the test item, ranging from 19% to 55%, were observed at 50°C over a period of 120 hours. However, as no chemical explanation could be given for the test item losses and the changes in study design (concentration , test container and sample preparation) lead to changes in the test item recovery, it was concluded that irreversible adsorption of the test item to the test container walls might be the most probable reason for test item elimination.
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