Registration Dossier
Registration Dossier
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EC number: 238-484-2 | CAS number: 14484-64-1
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Data for the definitive conclusion on the PBT or vPvB properties of Ferbam (CAS No. 144484-64-1) are available.
Persistence (P):
According to the criteria stated in Regulation (EC) 1907/2006, Annex XIII, persistence can be determined through the evaluation of the dissipation half-lives of a substance in different environmental compartments. Experimental data on the biodegradation of Ferbam in water and soil (aerob, anaerob) are available. Hydrolysis (half-lives of 7.8 minutes, 12.1 minutes and not determinable because degraded instantly at pH 5, 7 and 9) and photolysis data in water contribute significantly to the degradation of this substance in water. Ferbam is also rapidly degraded in soil systems, in which half-lives below 30 days were reported, respectively. Thus, the P criterion is not met for this substance.
Bioaccumulation (B):
Experimental data determining the Bio Concentration Factor (BCF) of Ferbam in aquatic organisms are not available. Nevertheless, the log Kow of the substance is considered as a good surrogate for the evaluation of the B criterion. Based on its log Kow value, below 3, Ferbam shows low potential for bioaccumulation. Therefore, this substance does not meet the B criterion.
Toxicity (T):
According to the criteria stated in Regulation (EC) 1907/2006, Annex XIII, the toxicity of a certain substance can be assessed based on the available toxicity data on aquatic organisms and mammals. The long-term study performed testing the chronic effects of Ferbam on fish species resulted in a NOEC value of 100 µg a.i./L (above 0.01 mg/L). However, this substance is classified as Skin Irrit. 2 - H315; Eye Irrit. 2 - H319; STOT SE 3 - H335; Aquatic Acute 1 - H400; Aquatic Chronic 1 - H410; Acute Tox. 2 - H330 and Skin Sens. 1 - H317 and therefore it can be considered as T.
Reference
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