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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

Description of key information

The biodegradability of the test substance was investigated in a GLP guideline study similar to OECD 301F (BASF AG 486504, 1986). After a test duration of 28 days, a biodegradation of 40 -50% (based on oxygen consumption) was determined. Based on this result, the test substance is considered to be "not readily biodegradable according to OECD criteria", but the results indicate that the substance has a significant potential for inherent biodegradation.


The outcome of the ready biodegradability study is supported by a inherent biodegradability study according to OECD 302B, in which a DOC removal of 56% was measured after a test duration of 28 days (BASF AG 1986). 


In addition, the biodegradation potential of all relevant known constituents of the test substance was assessed using an in-silico approach (supporting study; Klimisch reliability score of 2), the BOD QSAR Model “LMC OASIS CATALOGIC 301C”. This model also identifies the biotic degradation products of the test substance. The in silico approach was chosen as the most appropriate method to assess the degradation products considering that the parent substance is a complex UVCB consisting of several known constituents. primary half-life values ranged from to 4.78 to 17.86 days and ultimate half-life values ranged from 19.85 to 28.21 days. These results indicate that none of the assessed substances (parent substances and degradation products) are likely to persist in the environment. 

Key value for chemical safety assessment

Biodegradation in water:
inherently biodegradable, not fulfilling specific criteria
Type of water:

Additional information