Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 946-420-6 | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- adopted on 27 July 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 30 May 2008
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- static method
- Temp.:
- 20 °C
- Vapour pressure:
- 1.6 hPa
- Conclusions:
- The vapour pressure of polyglycerin caprylate/caprinate was 1.6 hPa at 20°C.
- Executive summary:
The vapour pressure of polyglycerin caprylate/caprinate was determined according to OECD Guideline 104 (1995) and EU method A.4 (2008) using the static method. The vapour pressure at 20°C was 1.6 hPa. The sample was heated for 2,5 h in vacuum at 50 °C to remove residual water. No control of completeness of removing was possible. So the result might show a vapour pressure which is generated by rest of water.
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- 1. SOFTWARE
EpiSuite V4.11
2. MODEL (incl. version number)
MPBPVP v1.43
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
O=C(CCCCCCCCC)OCC(O)COCC(O)COCC(O)CO (polyglycerin-3 caprylate)
C(O)(COCC(O)COCC(O)CO)CO (polyglycerol-3)
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
see attached justification
5. APPLICABILITY DOMAIN
The substance is within the molecular weight range of the training set.
6. ADEQUACY OF THE RESULT
A very low vapour pressure has been expected based on the ionic structure of the substance. The obtained results are in line with the expectations. It is known, that the estimation error increases as the vapor pressure decreases, especially when the vapor pressure decreases below 0.0001333 Pa. - Principles of method if other than guideline:
- estimation of vapopur pressure using Episuite v4.11, MPBPWIN v1.43
- GLP compliance:
- no
- Type of method:
- other: QSAR (Episuite, MPBPWIN v1.43 )
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Antoine Method; polyglycerin-3 caprylate
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Modified Grain Method; polyglycerin-3 caprylate
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Mackay Method; polyglycerin-3 caprylate
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Antoine Method; polyglycerol-3
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Modified Grain Method; polyglycerol-3
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Mackay Method; polyglycerol-3
- Conclusions:
- The vapour pressure of polyglycerin caprylate/caprinate was estimated to be <2.33E-05 Pa (MPBPWIN v1.43; Mackay Method).
Referenceopen allclose all
Temperature [°C] |
Vapour pressure [hPa] |
20.0 |
1.6 |
29.5 |
2.8 |
39.19 |
4.7 |
48.93 |
8.0 |
68.78 |
21.5 |
88.25 |
49.0 |
108.3 |
100.1 |
128.0 |
184.6 |
147.7 |
317.6 |
143.0 |
278.8 |
138.0 |
244.2 |
Description of key information
1.6 hPa at 20°C (OECD TG 104)
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
The vapour pressure of polyglycerin caprylate/caprinate was determined according to OECD Guideline 104 (1995) and EU method A.4 (2008) using the static method. The vapour pressure at 20°C was 1.6 hPa. The sample was heated for 2.5 h in vacuum at 50 °C to remove residual water. No control of completeness of removing was possible. So the result might show a vapour pressure which is generated by rest of water.
Thus, in addition the vapour pressure of the substance was estimated using Episuite v4.11, MPBPWIN v1.43 resulting in values </=2.33E-05 Pa (Mackay Method).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
