Registration Dossier
Registration Dossier
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EC number: 423-800-5 | CAS number: 7305-71-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-amino-5-methylthiazole
- EC Number:
- 423-800-5
- EC Name:
- 2-amino-5-methylthiazole
- Cas Number:
- 7305-71-7
- Molecular formula:
- C4 H6 N2 S
- IUPAC Name:
- 5-methyl-1,3-thiazol-2-amine
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The biodegradation rates ranged fram +7 % to -12 % throughout the 28-day exposure period.
Therefore, 2-AMINO-5-METHYLTHIAZOL proved to be nondegradable within 28 days.
Furthermore, 2-AMINO-5-METHYLTHIAZOL showed no inhibitory or toxic effect on microrganisms up to a test concentration of 10 mg/I.
The reference compound, Aniline, was readily degraded by 69 % within 14 days and by 60 % within 28 days.
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