alumina doped with cobalt

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Not reported

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline study (OECD 105)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

Aluminum oxide

IUPAC Name:

Aluminum oxide

Constituent 2

Reference substance name:

Aluminium oxide

EC Number:

215-691-6

EC Name:

Aluminium oxide

Cas Number:

1344-28-1

Molecular formula:

Al2O3

IUPAC Name:

dialuminium trioxide

Details on test material:

Description: white powder
Purity > 98.5%
Batch No. 21/2009
Date recevied: 27Oct2009
Storage: room temperature in dar

Results and discussion

Water solubility

Water solubility:

<= 0 g/L

Temp.:

20 °C

pH:

ca. 6 - ca. 7

Any other information on results incl. tables

Table 4.3

Sample No.	Time shaken at 30 C (hr)	Time equilibrated at 20C (hr)	Concentration (g/L)	pH
1	24	24	≤ 0.00002	6.8
2	48	24	≤ 0.00002	6.8
3	72	24	≤ 0.00002	6.8

mean concentration = 0.00002 g/L at 20 deg C

ICP analysis table from BLL:

BLL ref No.	Sample ID	Al mg/L
BL-11-0535-09	Sample 1A	0.02
BL-11-0536-09	Sample 1B	0.02
BL-11-0537-09	Sample 2A	0.02
BL-11-0538-09	Sample 2B	0.02
BL-11-0539-09	Sample 3A	0.02
BL-11-0540-09	Sample 3B	0.02
BL-11-0541-09	Blank A	0.02
BL-11-0542-09	Blank B	0.01

Per Appendix 1 page 3 (Walker JA, Butterworth Laboratories, BLL report No 0911-0058):

Reference items: 1000 ppm stock aluminum standard supplied by Romil, Product E3AL6 Lot L546487 and 10000 ppm aluminum stock supplied by Romil, Product N7AL6 Lot E534457

In house method BLM55G issue 17. Discussion of ICP results: instrument was calibrated over range 0.1 to 10 mg/L. A 1 ppm QC check standard was run at the end of the sequence. Results for this standard fell within 95 -105% of target. In-house duplicate tests were not performed as duplicate sampes were prepared prior to receipt. Limit of detection was assessed by preparing a standard at 0.01 mg/L. The readings were made that generated a mean of 0.008 mg/L with a 5% RSD. The theoretical limit of detection was estimated at 0.004 mg/L (10X std dev). Based on this data, a reporting limit of 0.01 mg/L was considered acceptable.

Applicant's summary and conclusion

Conclusions:

The water solubility of aluminum oxide as determined by the OECD Guideline 105 was <0.00002 g/L, which is insoluble.

Executive summary:

The water solubility of aluminum oxide was less than or equal to 2x10-5 g/L of solution at 20.0 +/- 0.05 degrees C, withing the pH range 6 to 7 in accordance with the flask method, of the OECD Guidelines for Testing of Chemicals. Aluminum oxide is insoluble.