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EC number: 308-964-7
CAS number: 99328-47-9
Clinical observations and mortality: no mortality and no signs of
systemic toxicity were noted in the test and control animals during the
Weight evolution: bodyweight changes of the test animals between Day 1
and Day 6 were comparable to those observed in the corresponding control
group animals over the same period.
Estimation of the proliferative response of lymph node cells: the
Stimulation Index (SI) calculated by individual approach was 1.30, 0.96
and 0.91 for the treated groups at 5%, 10% and 20%, respectively.
Therefore, the EC1.6 cannot be determined due to the absence of SI value
higher than 1.6.
Local irritation: slight dryness of the skin was noted in all animals
treated on day 6. An increase in ear weight (+21.3%, +18.8% and +3.0%)
was noted in animals treated at 5%, 10% and
20% respectively. Therefore, the test item has to be considered as not
excessively irritant at these concentrations, in accordance with the
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