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Sedolisin was found not to be toxic to Daphnia magna at a nominal concentration up to 100 mg TOS/L (24.7 mg aep/L) after 48h exposure. Thus, no 48h EC50 could be calculated and must be > 100 mg TOS/L (> 24.7 mg aep/L).

Sedolisin was not toxic to Pseudokirchneriella subcapitata up to a concentration of 100 mg TOS/L (24.7 mg aep/L) as no significant growth inhibition was observed in the present test system. Thus no 72h ErC50 could be calculated and must be > 100 mg TOS/L (> 24.7 mg aep/L). NOEC was determined to be 10 mg TOS/L (2.5 mg aep/L).

Sedolisin was tested in concentrations 10, 30, 50, 70, 100 TOS mg/L. It was found to inhibit growth rate at all concentrations tested after 72h exposure, whereas no significant inhibition was observed after 24 and 48h exposure. Inhibition of the growth rate at 72h was found to be approximately 3% at 10 mg TOS/L, 34 % at 30 mg TOS/L, 30% at 50 mg TOS/L, and 12 % at 100 mg TOS/L indicating only slightly toxicity towards algal growth. There was no dose-response relationship and because of the low observed toxicity towards algal growth no ErC50 value could be estimated and must be > 100 mg TOS/L (> 24.7 mg aep/L). The NOEC value was determined to be > 10 mg TOS/L (> 2.5 mg aep/L).

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