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EC number: 231-162-2 | CAS number: 7440-54-2
The acute oral toxicity of the test material was investigated in accordance with the standardised guidelines OECD 420 and EU Method B1 bis, under GLP conditions. The fixed dose procedure was performed in female Wistar strain rats.
Following a sighting test at dose levels of 300 mg/kg and 2000 mg/kg, a further group of four fasted females was given a single oral dose of test material, as a suspension in arachis oil BP, at a dose level of 2000 mg/kg body weight. Clinical signs and body weight development were monitored during the study. All animals were subjected to gross necropsy.
There were no deaths or signs of systemic toxicity, all animals showed expected gains in body weight and no abnormalities were noted at necropsy.
Under the conditions of this study, the oral LD50 value in female Wistar rats was established to exceed 2000 mg/kg body weight.
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