Registration Dossier
Registration Dossier
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EC number: 612-975-5 | CAS number: 6225-08-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 July 2019 - 04 Nov 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- GLP compliance:
- yes (incl. QA statement)
- Test type:
- other: Limit test
- Limit test:
- yes
Test material
- Reference substance name:
- N,N-dimethylnonanamide
- EC Number:
- 612-975-5
- Cas Number:
- 6225-08-7
- Molecular formula:
- C11H23NO
- IUPAC Name:
- N,N-dimethylnonanamide
- Details on test material:
- - Name of test material (as cited in study report): N,N-Dimethylnonanamide
- Synonyme: Genagen PA
1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: aerosol
- Type of inhalation exposure:
- nose only
- Concentrations:
- 2.26 mg/L
- No. of animals per sex per dose:
- 3
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 2.26 mg/L air
Any other information on results incl. tables
No treatment related clinical signs of toxicity and mortalities were observed. Slight decrease in body weight was noted on Day 2 due to exposure. All animals showed increase in body weight on day 4, 8 and 15.
No treatment related gross pathological findings were observed at the mean analytical achievable concentration of 2.26 mg/L of air.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute inhalation toxicity of the registration substance Genagen PA/N.N-Dimethylnonamide was investigated according to the OECD Guideline 403. At the liquid aerosol concentration of 2.26 mg/l, no effect was found. The LD50 is higher than 2.26 mg/l.
- Executive summary:
The acute inhalation toxicity of the registration substance Genagen PA/N.N-Dimethylnonamide was investigated according to the OECD Guideline 403. At the liquid aerosol concentration of 2.26 mg/l, no effect was found. The LD50 is higher than 2.26 mg/l.
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