Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.088 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.881 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.009 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor
PNEC marine water (intermittent releases):
0.088 mg/L

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
10 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.405 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.041 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.028 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

- Short-term toxicity to fish: Key study: OECD 203 and EU method C.1. GLP study. The 96h-EC50 of the test item in zebrafish was found to be higher than 88.14 mg/L (measured) and the NOEC was 88.14 mg/L (measured), both based on mortality.

- Short-term toxicity to aquatic invertebrates: Key study: OECD 202 and EU C.2. GLP study. The 48h-EC50 of the test item in Daphnia magna was found to be higher than 100 mg/L and the NOEC was 100 mg/L, both based on mobility.

- Toxicity to aquatic algae and cyanobacteria: Key study: OECD 201 and EU method C.3. GLP study. The 72h-EC50 of the test item in green algae Pseudokirchneriella subcapitata was found to be higher than 100 mg/L and the NOEC was determined to be 100 mg/mL, both based on growth rate.

- Toxicity to microorganisms: Key study: OECD 301F and EU method C.4-D. GLP study. The test item was not inhibitory to microorganism growth at a dose of 100 mg/L. Therefore, it can be concluded a NOEC of 100 mg/l.

Conclusion on classification

Based on available data (96h-EC50 in fish > 88.14 mg/L, 48h-EC50 in Daphnids > 100 mg/L, 72h-EC50 in algae > 100 mg/L) and since the substance is readily biodegradable, with a Log Kow < 4, the test item is not classified for aquatic toxicity, according to CLP regulation (EC) No. 1272/2008.