Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-406-8 | CAS number: 106-52-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction
- Guideline:
- other: REACH Guidance on (Q)SAR
- Principles of method if other than guideline:
- (Q)SAR
- Test organisms (species):
- other: Green algae
- Test type:
- other: (Q)SAR
- Water media type:
- freshwater
- Dose descriptor:
- other: Chronic Value (ChV)
- Effect conc.:
- 19.578 mg/L
- Validity criteria fulfilled:
- yes
- Remarks:
- Aliphatic Amines: Maximum LogKow: 7.0 (Chronic Value)
- Conclusions:
- Estimated Chronic Value : 19 mg/L
Intermediate substance is not estimated to be toxic to aquatic algae. - Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- not specified
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- TEST ORGANISM
- Age of inoculum (at test initiation): 72h
- Concentration: 1.6 E 6 c/ml - Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
- pH:
- 8.9
- Nominal and measured concentrations:
- test done at 1 mg/L, 10 mg/L and 100 mg/L
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 - < 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Conclusions:
- 10.00 mg/L < CEr50 - 72h < 100.00 mg/L
The intermediate is harmful for Algae
Referenceopen allclose all
Description of key information
Short-term toxicity:
Study result: 10.00 mg/L < CEr50 - 72h < 100.00 mg/L
The intermediate is harmful for Algae
Long-term toxicity:
Indicated results for chronic toxicity are "Chronic values" as obtained from ECOSAR 1.11
ECOSAR 1.11: Green Algae: ChV: 19.578 mg/L
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 19 mg/L
Additional information
NOEC could be estimated to around 13 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)
Intermediate substance is estimated to be harmful to aquatic algae (Acute toxicity).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
