Registration Dossier
Registration Dossier
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EC number: 944-067-2 | CAS number: -
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
No experimental short-term toxicity tests for algae and Daphnia are available for the substance. ECOSAR predictions (using measured log Kow = 3.8) resulted in an EC50 value for Daphnia of 2.4 mg/l, whereas the ErC50 for algae is 3.5 mg/L. Based on the lowest available acute data for Daphnia with an EC50 value of 2.4 mg/L the substance does not need to be classified for acute aquatic toxicity according to Table 4.1.0 (a) of CLP.
As only one chronic value is available (algae EC10 = 1.3 mg/L), the aquatic chronic classification needs to be derived on both chronic and acute toxicity data and the most stringent outcome needs to be taken into consideration. The chronic value available is the ErC10 for algae being 1.3 mg/L. In combination with the substance not being readily biodegradable this would not lead to classification according to Table 4.1.0 (b) (i) of CLP. In view of the acute daphnid result of 2.4 mg/L, the substance not being readily biodegradable and the log Kow of 3.8 the substance needs to be classified for long term aquatic toxicity according to Figure 4.1.1 and Table 4.1.0, (b) iii of CLP, resulting in Aquatic Chronic Category 2 (H411) classification.
Overall, it can be concluded that Dimeth Cyclormol needs to be classified as Aquatic Chronic 2 (H411) in accordance with the criteria outlined in EU CLP (EC/1272/2008 and its updates).
Additionally, in view of the acute toxicity data (>1 but <=10 mg/L), the substance should be classified for acute aquatic hazard resulting in Category Acute 2 (H401) according to GHS.
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