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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
OECD 107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

1
Chemical structure
Reference substance name:
disodium 2,4-dihydroxy-5-[(2-hydroxy-3-nitro-5-sulphonato-phenyl)azo]benzoate, reaction products with chromium triacetate
Molecular formula:
not applicable
IUPAC Name:
disodium 2,4-dihydroxy-5-[(2-hydroxy-3-nitro-5-sulphonato-phenyl)azo]benzoate, reaction products with chromium triacetate

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
-3.77
Temp.:
23 °C
pH:
ca. 6
Remarks on result:
other: mean of 6 measurements

Any other information on results incl. tables

Table 1: Results

no.

stock solution [mL]

n-octanol [mL]

conc. in n-octanol phase [mg/L]

conc. in water phase [mg/L]

log pow

A1

5

10

0.14

756.1

- 3.75

A2

5

10

0.13

767.6

- 3.78

B1

10

10

0.14

760.0

- 3.75

B2

10

10

0.12

757.9

- 3.80

C1

20

10

0.13

749.7

- 3.77

C2

20

10

0.14

761.1

- 3.75

mean

-

-

-

-

- 3.77

Stock solution: 847 mg/L = 758.9 mg/L active substance

The recovery rate of the test substance was between 99 % and 101 %.

Applicant's summary and conclusion