Registration Dossier
Registration Dossier
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EC number: 609-425-1 | CAS number: 374067-80-8
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient documentation for an assessment of reliability.
- Reason / purpose for cross-reference:
- reference to same study
- Principles of method if other than guideline:
- An excess of product is shaked with solvent during 24 hours at 20 deg C. After filtration the concentration in solution is determined with spectrometry.
- GLP compliance:
- not specified
- Medium:
- methanol
- Solubility:
- 1.1 g/L
- Temp.:
- 20 °C
- Medium:
- ethanol
- Solubility:
- 1.2 g/L
- Temp.:
- 20 °C
- Medium:
- other: 2-propanol
- Solubility:
- 0.63 g/L
- Temp.:
- 20 °C
- Medium:
- other: 2-propanone
- Solubility:
- 0.32 g/L
- Temp.:
- 20 °C
- Medium:
- other: N,N-dimethylacetamide
- Solubility:
- 160 g/L
- Temp.:
- 20 °C
- Medium:
- dimethylformamide
- Solubility:
- 68 g/L
- Temp.:
- 20 °C
- Medium:
- other: acetic acid
- Solubility:
- 1.1 g/L
- Temp.:
- 20 °C
- Details on results:
- no data
- Conclusions:
- The solubility of T002326 in different kinds of organic solvents ranges from 0.32 g/L in 2-propanone to 160 g/L in N,N-dimethylacetamide.
Reference
Description of key information
A K4 supporting study reports various solubilities of test substance in different organic solvents (K4, J&J PRD, 2005).
Key value for chemical safety assessment
Additional information
| solvent | solubility g/L (20°C) |
| methanol | 1.1 |
| ethanol | 1.2 |
| 2-propanol | 0.63 |
| 2-propanone | 0.32 |
| N,N-dimethylacetamide | 160 |
| N,N-demithylformamide | 68 |
| acetic acid | 1.1 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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