Registration Dossier
Registration Dossier
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EC number: 226-285-3 | CAS number: 5343-92-0
Carcinogenicity
Administrative data
Description of key information
1,2 pentanediol is non mutagenic in the Ames test (OECD 471) and the mouse lymphoma test (L5178Y TK +/-; OECD476). No clastogenicity was found in a chromosomal aberration test (OECD 473). Therefore 1,2 pentanediol is considered to be clearly non mutagenic. According to column 2 Annex Xit is not necessary to conduct a carcinogenicity study therefore. Beyond this there are no hints for a possible secondary cancer mechanism. 1,2 pentane diol therefore is expected to be non carcinogenic.
Key value for chemical safety assessment
Justification for classification or non-classification
Classification for carcinogenicity is not warranted according to the criteria of EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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