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EC number: 700-051-5 | CAS number: 35077-00-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 20 February 2008 - 28 February 2008.
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: fragment constant methodology
- Deviations:
- no
- Principles of method if other than guideline:
- An estimation was performed by a fragment constant methodology using the specialized chemical estimation software, KOWWIN, version 1.67, © 2000 US Environmental Protection Agency. The software was validated with reference substances which had common or similar functional groups present as the test material.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: Fragment Constant Methodology
- Partition coefficient type:
- other: Fragment Constant Methodology
Test material
- Reference substance name:
- diethyl(triethoxysilyl)amine
- EC Number:
- 700-051-5
- Cas Number:
- 35077-00-0
- Molecular formula:
- C10H25NO3Si
- IUPAC Name:
- diethyl(triethoxysilyl)amine
Constituent 1
Study design
- Analytical method:
- not specified
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 0.5
- Temp.:
- 20 °C
- Remarks on result:
- other: Calculation method used so temperature was not measured.
- Details on results:
- Using the software, the test material was estimated to have a partition coefficient (log10 Pow) of 0.50.
Any other information on results incl. tables
Please see Attachment 1 for all details on the software calculations.
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient was estimated by a fragment constant methodology using the specialized chemical estimation software, KOWWIN, version 1.67, © 2000 US Environmental Protection Agency. The estimation for the test material was log10 Pow 0.50.
- Executive summary:
No determination of partition coefficient by Method A8 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC) was possible.
From information supplied by the Sponsor, the test material was known to react with water (and water in the atmosphere). Such a reaction with water invalidated determination of the partition coefficient using the shake-flask method. The test material would also react with a mobile phase appropriate to the HPLC estimation method, invalidating this approach also. Additionally, no estimation of the partition coefficient could be calculated from the approximate solubility of the test material in n-octanol and water, as the visual assessment of the solubility in water would be inevitably influenced by hydrolysis.
In this particular investigation a Partition Coefficient study for U-donor (project number 1456 -0097) was performed by a fragment constant methodology using the specialized chemical estimation software, KOWWIN, version 1.67, © 2000 US Environmental Protection Agency. The software was validated with reference substances which had common or similar functional groups present as the test material.
The estimation for the test material was log10 Pow 0.50.
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