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EC number: 248-895-9 | CAS number: 28198-05-2
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic/sediment
Using Bio-concentration Factor (v12.1.0.50374) module Bio-concentration Factor over the entire pH scale (pH 0 -14) of the test substance 1,4 -bis[(4 -butylphenyl)amino]-5,8 -dihydroxy-9,10 -dihydroanthracene-9,10-dione (CAS no. 28198 -05 -2) was estimated to be > 1000000.0, 4146662, 391974, 11176, 1181, 955, 941 and 940 at pH 0-6, 7, 8, 9, 10, 11, 12 and 13-14, respectivelyACD (Advanced Chemistry Development)/I-Lab predictive module, 2017). This value indicates that the test substance 1,4 -bis[(4 -butylphenyl)amino] -5,8 -dihydroxy-9,10 -dihydroanthracene-9,10 -dione was considered to be accumulative in aquatic organisms.
Additional information
Bioaccumulation: aquatic/sediment
Various predicted data for the target compound1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy-9,10-dihydroanthracene-9,10-dione(CAS No. 28198-05-2) were reviewed for the bioaccumulation end point which are summarized as below:
In a prediction done by using Bio-concentration Factor (v12.1.0.50374) moduleACD (Advanced Chemistry Development)/I-Lab predictive module, 2017), theBCF over the entire pH scale (pH 0 -14) of the test substance 1,4 -bis[(4 -butylphenyl)amino]-5,8 -dihydroxy-9,10 -dihydroanthracene-9,10-dione (CAS no. 28198 -05 -2) was estimated to be > 1000000.0, 4146662, 391974, 11176, 1181, 955, 941 and 940 at pH 0-6, 7, 8, 9, 10, 11, 12 and 13-14, respectively.
Bioconcentration Factor (BCF) of test chemical 1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy-9,10-dihydroanthracene-9,10-dione (CAS no. 28198 -05 -2) was estimated using Chemspider database(ChemSpider, 2017). The bioconcentration factor of test substance 1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy-9,10-dihydroanthracene-9,10-dione was estimated to be 1000000.00 and 289710.13 at both pH 5.5 and 7.4, respectively.
Another predicted data was estimated usingSciFinder database (American Chemical Society (ACS), 2017) was used for predicting the bioconcentration factor (BCF) of test chemical (1,4 -bis[(4 -butylphenyl)amino]-5,8 -dihydroxy-9,10 -dihydroanthracene-9,10 -dione (CAS No. 28198 -05 -2). The bioconcentration factor (BCF) of 1,4 -bis[(4 -butylphenyl)amino]-5,8 -dihydroxy-9,10 -dihydro anthracene-9,10 -dione was estimated to be 1000000.0, 222000.0 and 23500 at pH range 1-8, 9 and 10, respectively (at 25 deg C).
On the basis of above results for target chemical1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy-9,10-dihydroanthracene-9,10-dione(from ACD labs,ChemSpider and SciFinder database, 2017), it can be concluded that the BCF value of test substance1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy-9,10-dihydroanthracene-9,10-dione ranges from 940 –4146662which exceeds the bioconcentration threshold of 2000, indicating that the chemical 1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy-9,10-dihydroanthracene-9,10-dione is expected to bioaccumulate in the food chain.
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