Resin acids and Rosin acids, ammonium salts

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

accepted calculation method

Justification for type of information:

Data is from EPI suite, ECOSAR version 1.1.

Qualifier:

according to guideline

Guideline:

other: Modeling database

Principles of method if other than guideline:

Prediction done using ECOSAR v.1.11 model

GLP compliance:

no

Specific details on test material used for the study:

- Name of the test material: Resin acids and Rosin acids, ammonium salts
- Regulatory name: Resin acids and Rosin acids, ammonium salts
- Molecular formula: Not specified
- Molecular weight: Not specified
- Substance type: Organic

Analytical monitoring:

no

Vehicle:

no

Test organisms (species):

other: Fish

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

2 346.61 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Remarks on result:

other: not toxic

Conclusions:

On the basis of EPI suite, ECOSAR version 1.1, the LC50 value for short term toxicity to fish was predicted to be 2346.61 mg/l for Resin acids and Rosin acids, ammonium salts in 96 hrs. Based on the LC50 value, it can be concluded that the substance Resin acids and Rosin acids, ammonium salts as not toxic to aquatic environment.

Executive summary:

On the basis of EPI suite, ECOSAR version 1.1, the LC50 value for short term toxicity to fish was predicted to be 2346.61 mg/l for Resin acids and Rosin acids, ammonium salts in 96 hrs. Based on the LC50 value, it can be concluded that the substance Resin acids and Rosin acids, ammonium salts as not toxic to aquatic environment and thus can be considered “not classified” per the CLP criteria for aquatic environment.

Description of key information

On the basis of EPI suite, ECOSAR version 1.1, the LC50 value for short term toxicity to fish was predicted to be 2346.61 mg/l for Resin acids and Rosin acids, ammonium salts in 96 hrs. Based on the LC50 value, it can be concluded that the substance Resin acids and Rosin acids, ammonium salts as not toxic to aquatic environment and thus can be considered “not classified” per the CLP criteria for aquatic environment.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

2 346.61 mg/L

Additional information

Following studies include the predicted data for the target chemical to conclude the toxicity extent of Resin acids and Rosin acids, ammonium salts (CAS: 68649-89-8) towards fish is summarized as follows:

On the basis of EPI suite, ECOSAR version 1.1, the LC50 value for short term toxicity to fish was predicted to be 2346.61 mg/l for Resin acids and Rosin acids, ammonium salts in 96 hrs. Based on the LC50 value, it can be concluded that the substance Resin acids and Rosin acids, ammonium salts as not toxic to aquatic environment and thus can be considered “not classified” per the CLP criteria for aquatic environment.

Similar result is available for the target which is done by using EPI suite, ECOSAR version 1.1, the LC50 value for short term toxicity to fish was predicted to be 2957.81 mg/l for Resin acids and Rosin acids, ammonium salts in 96 hrs. Based on the LC50 value, it can be concluded that the substance Resin acids and Rosin acids, ammonium salts as not toxic to aquatic environment and thus can be considered “not classified” per the CLP criteria for aquatic environment.

Thus based on the effect concentrations which is in the range 2346.61 mg/l to 2957.81 mg/l give the conclusion that test substance Resin acids and Rosin acids, ammonium salts (CAS: 68649-89) is likely to be non-toxic to aquatic algae at environmentally relevant concentrations and applying weight of evidence approach it can be considered to be“not classified”as per the CLP classification criteria.