Registration Dossier
Registration Dossier
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EC number: 202-718-1 | CAS number: 98-97-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from SRC PhysProp Database, ChemIDplus, EPI suite & DANISH Q(S)AR database
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- Estimation of octanol water partition coefficient of the test substance Pyrazine-2-carboxylic acid.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- - Name of test material: Pyrazinoic acid
- Molecular formula: C5H4N2O2
- Molecular weight: 124.099 g/mol
- Smiles notation: c1ncc(C(=O)O)nc1
- InChl: 1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9)
- Physical state: Solid - Key result
- Type:
- log Pow
- Partition coefficient:
- -0.18
- Remarks on result:
- other: Other details not known
- Details on results:
- The LogPow of the test chemical Pyrazine-2-carboxylic acid was estimated to be -0.18.
- Conclusions:
- The partition coefficient (log Pow) value of the substance Pyrazine-2-carboxylic acid was estimated to be -0.18.
- Executive summary:
The partition coefficient (log Pow) value of the substance Pyrazine-2 -carboxylic acid was estimated to be -0.18. Based on the estimated value, the chemical Pyrazine-2-carboxylic acid can be considered to be hydrophilic in nature.
Reference
Description of key information
Based on the available data from authoritative databases, the partition coefficient (log Pow) value of the substance Pyrazine-2-carboxylic acid was estimated to be -0.18. Based on the estimated value, the chemical Pyrazine-2 -carboxylic acid can be considered to be hydrophilic in nature.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.18
Additional information
Based on the available data from authoritative databases, the partition coefficient (log Pow) value of the substance Pyrazine-2-carboxylic acid was estimated to be -0.18. Based on the estimated value, the chemical Pyrazine-2 -carboxylic acid can be considered to be hydrophilic in nature.
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