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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
Weight of evidence approach based on available experimental data as well as predicted data.
Principles of method if other than guideline:
Estimate by WSKOWWIN v1.42 as implemented in EPI Suite v4.11.
Water solubility:
< 0.024 mg/L
Temp.:
25 °C
Remarks on result:
other: estimated using no-melting point equation
Conclusions:
Estimated water solubility at 25 °C is 0.024 mg/l.
Executive summary:

Method

Estimate of partition coefficient carried out by WSKOWWIN v1.42 as implemented in EPI Suite v4.11.

Results

Estimated water solubility at 25 °C is 0.024 mg/l.

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
December 23, 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Water solubility:
< 0.02 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
ca. 6.76
Remarks on result:
other: pH mother solution = 6.83; pH satured solution = 6.76
Conclusions:
Average solubility: < 0.02 g/l (20 °C; pH 6.76 satured solution).
Executive summary:

Method

Solubility test was performed following OECD guideline 105.

Result

Average solubility: < 0.02 g/l at 20 °C and pH 6.76 of satured solution.

Description of key information

Not soluble.

Key value for chemical safety assessment

Water solubility:
0.024 mg/L
at the temperature of:
25 °C

Additional information