Registration Dossier
Registration Dossier
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EC number: 500-078-0 | CAS number: 31923-84-9 1 - 4.5 moles propoxylated
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to microorganisms is determined to give a 3 h-EC50 > 10.000 mg/L (Bayer, 2002 and Bayer, 2003).
Key value for chemical safety assessment
Additional information
Hypothesis for the read-across approach:
Group: Succhrose, propoxylated; Propylidynetrimethanol, propoxylated; Glycerol, propoxylated; D‑Glucitol, propoxylated; Propane-1,2-diol, propoxylated; Pentaerythritol, propoxylated; 2,2',2''‑Nitrilotriethanol, propoxylated; Trimethylolpropane, ethoxylated; Diethylene glycol, propoxylated; Ethylene glycol, propoxylated; Diethanolamine, propoxylated.
The substance is member of a group of chemicals with similar chemical structure and physical behaviour:
1.) Chemical similarity: All of these substances have terminal OH-groups and ether-linkages as common structural features. Thus, the substances differ from each other only in the identity/type of starter molecule (aliphatic alcohols with 2 to 8 hydroxy functions) used and its associated bonding with the alkoxylate repeating units. Typically the products are substances with a range of Ethyleneoxide or Propyleneoxide units (1 -12.5) added to starter molecules. All substances are characterised by a molecular weight distribution of ca. 150 - 1000. The common function of the members of the group is to allocate a high number of hydroxy functions which are intended to react with e. g. an isocyanate.
2.) Physical behaviour: All members of the group are liquids with elevated viscosity, high solubility in water (> 100 g/L) and a low vapour pressure (<10E-04 hPa).
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