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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
other: Biomonitoring study: IUCLID 4 migrated data set
Rationale for reliability incl. deficiencies:
other: Biomonitoring study.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Biomonitoring of Urinary Aromatic Amines and Arylamine Haemoglobin Adducts in Exposed Workers and Non-Exposed Control Persons
Author:
Riffelmann M. et al.
Year:
1995
Bibliographic source:
Dokladi-Bulgarskata Akademiia Naukite 48, 79-82 (1995)
Reference Type:
publication
Title:
Unnamed
Year:
1995

Materials and methods

Study type:
other: study with workers exposed to arylamines; Biomonitoring
Principles of method if other than guideline:
method: other: Biomonitoring
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1,5-naphthylenediamine
EC Number:
218-817-8
EC Name:
1,5-naphthylenediamine
Cas Number:
2243-62-1
Molecular formula:
C10H10N2
IUPAC Name:
1,5-naphthylenediamine
Details on test material:
no data

Method

Type of population:
occupational
Ethical approval:
not specified
Route of exposure:
other: Biomonitoring
Reason of exposure:
intentional, occupational
Exposure assessment:
not specified

Results and discussion

Clinical signs:
Biomonitoring study: IUCLID 4 migrated data set

Any other information on results incl. tables

RM-Freetext:
1,5-naphthylenediamine was shown in the urine of workers
exposed to aromatic amines.

Applicant's summary and conclusion

Executive summary:

In a biomonitoring study 1,5-naphthylenediamine was shown in the urine of workers exposed to aromatic amines.