Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

The ready biodegradability of the test item 1,2,3-Propanetricarboxylic acid, 2-Hydroxy-, tris(C12-C13-branched-alkyl)ester was determined with a non-adapted activated sludge over a test period of 49 days in the Modified Sturm Test.

The test item 1,2,3-Propanetricarboxylic acid, 2-Hydroxy-, tris(C12-C13-branched-alkyl)ester is classified as not readily biodegradable, but inherently biodegradable (without pre-adaptation) and with the potential for complete mineralization.

The BCFBAF version 3.01 programme of the EPI Suite software (v 4.10) was used to predict either a log BCF of 0.5 (BCF of 3.16 L/kg) based on a regression estimate or a log BAF of - 0.05 (BAF of 0.893 L/kg) based on the Arnot-Gobas upper trophic model both using the smiles codes of tristridecyl 2 -hydroxypropane-1,2,3 -tricarboxylate and trisdodecyl 2 -hydroxypropane-1,2,3 -tricarboxylate representing the components of 1,2,3-Propanetricarboxylic acid, 2-Hydroxy-, tris(C12-C13-branched-alkyl)ester. Because the Arnot-Gobas upper trophic model takes also into account metabolism of the substance by the organism it is lower. The QSAR-data are supported by the results of the pharmacokinetics. 1,2,3-Propanetricarboxylic acid, 2-Hydroxy-, tris(C12-C13-branched-alkyl)ester will be hydrolysed, absorbed and efficiently metabolised into water soluble metabolites, which is supported by the molecular structure of 1,2,3-Propanetricarboxylic acid, 2-Hydroxy-, tris(C12-C13-branched-alkyl)ester and its physico-chemical properties.

It is concluded that 1,2,3-Propanetricarboxylic acid, 2-Hydroxy-, tris(C12-C13-branched-alkyl)ester will not accumulate in the body.

Additional information