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Physical & Chemical properties

Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to
OECD Guideline 105 (Water Solubility)
GLP compliance:
Type of method:
flask method
Water solubility:
26.96 g/L
Conc. based on:
test mat.
20 °C
ca. 7.71

Test results

Reference solutions were measured in the spectrophotometer in quantitative mode, thus generating a calibration curve. Calibration curve was smooth and linear at every concentration. Considering that preliminary test resulted in an absorbance keeping the same shape like the references, its value was considered for the 24 hours’ measurement (test 1). Due to the significant decrement of Test 3’s concentration at 96 hs, only test 1 and test 2 were considered for the average solubility. Adjusting concentrations in proportion to the real weights the following results were obtained:

test 1

(24 hs)  

26.84 g/l

test 2

(48 hs) 

27.08 g/l
average solubility 26.96 g/l
standard deviation 0.12    
test 3 (96 hs) 7.09    g/l
pH mother solution 6.42    
pH satured solution 7.71    
Under test conditions, the substance resulted as very soluble in water.
Executive summary:


Solubility test was performed following OECD guideline 105.


Average water solubility was 26.96 g/l at 20 °C and pH 7.71.

Description of key information

Not soluble at 20 °C and pH 6.21.

Key value for chemical safety assessment

Additional information

Water solubility according to OECD guideline 105.