Registration Dossier
Registration Dossier
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EC number: 203-406-8 | CAS number: 106-52-5
Endpoint summary
Administrative data
Description of key information
Hydrolysis:
The
estimated half-life of 1-methylpiperidin-4-ol was estimated to be 74.90
days, indicating that it is very negligibly hydrolysable.
Additional information
Hydrolysis:
Predicted
data for test compound4-Piperidinol, 1-methyl-(CAS No. 106-52-5) and its
read across substance for the hydrolysis end point which is summarized
as below:
The Hydrolysis of 1-methylpiperidin-4-ol was predicted using OECD QSAR toolbox version 3.3 (2017). The estimated half-life of 1-methylpiperidin-4-ol was estimated to be 74.90 days.
In supporting study for RA, Hydrolysis of substance Aziridine was studied at neutral pH (7). The half-life of Aziridine was determined to be 154 days.
Base on the above values indicates that the test substance 1-methylpiperidin-4-ol is very negligibly hydrolysable.
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