Registration Dossier
Registration Dossier
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EC number: 200-831-0 | CAS number: 75-01-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Handbook data are considered to be from a trusted source
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Registry of Toxic Effects of Chemical Substances
- Author:
- R.J. Lewis, R.L. Tatken
- Year:
- 1 979
- Bibliographic source:
- U.S. Dept. Health and Human Services, NIOSH
- Reference Type:
- review article or handbook
- Title:
- OECD SIDS "Vinyl Chloride"
- Author:
- American Chemistry Council, Wendy Sherman
- Year:
- 2 001
- Bibliographic source:
- UNEP Publications, Bern, p. 3 - ECOSAR
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
- GLP compliance:
- not specified
- Test type:
- fixed dose procedure
Test material
- Reference substance name:
- Chloroethylene
- EC Number:
- 200-831-0
- EC Name:
- Chloroethylene
- Cas Number:
- 75-01-4
- Molecular formula:
- C2H3Cl
- IUPAC Name:
- chloroethene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Lewis
- Sex:
- male/female
Results and discussion
Effect levelsopen allclose all
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 500 mg/kg bw
- Based on:
- test mat.
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 4 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
