Registration Dossier
Registration Dossier
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EC number: 229-398-6 | CAS number: 6507-79-5
Endpoint summary
Administrative data
Description of key information
LD50(oral) = 4955 mg/kg b.w
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Quality of whole database:
- This study was chosen because is good described and shows the signs of toxicity and good curve dose/response.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Acute toxicity assessment:
The assessment was based on a single study performed by oral administration in 1973 and conducted with unknown method. The purity of substance was about 90 %. The substance shows mortality for concentrations above 1000 mg/kg. The clinical signs were seen above 3000 mg/kg bw. The rats showed reduction in spontaneous motility, slight ataxia, diarrhea. Ditto and hypoventilation were observed for concentration of 10000 and 15000 mg/kg b.w.
Justification for classification or non-classification
Acute toxicity means those adverse effects occurring following oral or dermal administration of a single dose of a substance or a mixture, or multiple doses given within 24 hours, or an inhalation exposure of 4 hours.
No symptoms has been registered and no mortality has been observed for concentrations above 1000 mg/kg. The LD50 for oral administration is 4995 mg/kg b.w, therefore no classification for acute toxicity oral is warranted under the CLP Regulation (EC n. 1272/2008).
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