Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
basic toxicokinetics, other
Remarks:
Toxicokinetic assumption
Type of information:
other: Toxicokinetic assumption
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Toxicokinetic assumption
Objective of study:
other: Toxicokinetic assumption
Principles of method if other than guideline:
Toxicokinetic assumption
GLP compliance:
no

Description of key information

The data from the acute oral and repeated dose toxicity studies indicate no or a low absorption by the oral route based on the acute oral discriminating dose for male and female rats of 2000 mg/kg body weight and the NOAEL of 1000 mg/kg bw in the Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test.

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential

Additional information