Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: other route
Remarks:
other: repeated dose toxicity studies
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Bandman, A., L.; et al.
Year:
1994
Bibliographic source:
Vredny Chimiceskie Galogen, Chima, 394-395

Materials and methods

Principles of method if other than guideline:
other: 30 day and 4 months repeated dose toxicity study (application way ?)

Test material

Constituent 1
Chemical structure
Reference substance name:
Cyclohex-3-ene-1-carbaldehyde
EC Number:
202-858-3
EC Name:
Cyclohex-3-ene-1-carbaldehyde
Cas Number:
100-50-5
Molecular formula:
C7H10O
IUPAC Name:
cyclohex-3-ene-1-carbaldehyde

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
unspecified
Duration of treatment / exposure:
4 months
Doses / concentrations
Remarks:
Doses / Concentrations:
4 months toxicity study: 5, 22, 53 mg/m3, 30 day toxicity study: 1/5 LD50
No. of animals per sex per dose:
no data

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

4 months studies: Clinical signs: effects on the CNS, reduced activity of aldolase and katalase, adverse effects on different organs like brain, liver, kidney, lung

Applicant's summary and conclusion