Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only short abstract available

Data source

Materials and methods

Principles of method if other than guideline:
not stated
GLP compliance:
not specified
Test type:
other: not stated

Test animals

Species:
mouse
Strain:
other: Crlj:CD1(ICR)
Sex:
male

Administration / exposure

Vehicle:
water
Remarks:
deionizied water
Doses:
50 mg/kg bw
300 mg/kg bw
No. of animals per sex per dose:
five animals per dose level
Control animals:
yes

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 300 mg/kg bw
Based on:
other: ordinary substance
Mortality:
No animal died in any group.
Clinical signs:
other: General clinical Prone position was observed in each three animals of the 300 mg/kg at 60 minutes after administration, this symptom disappeared after that.
Gross pathology:
No macroscopic abnormalities were observed.

Applicant's summary and conclusion