Registration Dossier
Registration Dossier
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EC number: 943-084-2 | CAS number: -
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- genetic toxicity in vitro
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study has been judged as reliable with restrictions since it was conducted by a QSAR model.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR
- Title:
- In-vivo mutagenicity (Micronucleus) alerts by ISS
- Author:
- QSAR Toolbox 3.3.5.17
- Year:
- 2 016
- Bibliographic source:
- QSAR Toolbox 3.3.5.17
- Report date:
- 2016
Materials and methods
- Principles of method if other than guideline:
- QSAR Toolbox was used to determine the mechanistic profile of the substance.
Test material
- Reference substance name:
- Salt of 4-azidobutan-1-amine and (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonic acid
- EC Number:
- 943-084-2
- Molecular formula:
- C14H26N4O4S
- IUPAC Name:
- Salt of 4-azidobutan-1-amine and (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonic acid
- Reference substance name:
- NCCCCN=[N+]=[N-].CC1(C)C2CCC1(CS(O)(=O)=O)C(=O)C2
- IUPAC Name:
- NCCCCN=[N+]=[N-].CC1(C)C2CCC1(CS(O)(=O)=O)C(=O)C2
Constituent 1
Constituent 2
Results and discussion
Test results
- Genotoxicity:
- other: inconclusive
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
other: inconclusive
QSAR Toolbox identifies a structural alert of concern; in particular for in vivo mutagenicity (Micronucleus) alerts by ISS this altert is "Azide and triazine groups".
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