Registration Dossier
Registration Dossier
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EC number: 209-057-8 | CAS number: 554-00-7
Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Basic data given
Data source
Reference
- Reference Type:
- publication
- Title:
- Comparison of the susceptibility of 11 freshwater species to 8 chemical compounds II. (Semi)Chronic toxicity tests.
- Author:
- Slooff W, Canton JH
- Year:
- 1 983
- Bibliographic source:
- Aquat Toxicol 4: 271 - 282
Materials and methods
- Principles of method if other than guideline:
- toxicity test on the amphibian Xenopus laevis
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,4-dichloroaniline
- EC Number:
- 209-057-8
- EC Name:
- 2,4-dichloroaniline
- Cas Number:
- 554-00-7
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 2,4-dichloroaniline
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Xenopus laevis
- Details on test organisms:
- - Age at study initiation: < 2 days
- Feeding during test
- Food type: Neattle powder, heart
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 100 d
Test conditions
- Test temperature:
- 20 ± 1 °C
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per group (vessel): 75
- Test volume per group: 50 l
- Test medium: Dutch Standard Water (DSW)
OTHER TEST CONDITIONS
- Photoperiod: circadic
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
- mortality
- development
- growth
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 100 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 100 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.32 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: development
- Duration:
- 100 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
