Registration Dossier
Registration Dossier
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EC number: 921-798-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
- Acute oral toxicity: ACD/Percepta predicted for ADPA an acute oral LD50 to mouse equal to 1000 mg/kg and an acute oral LD50 to rat equal to 750 mg/kg.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 750 mg/kg bw
- Quality of whole database:
- Two ACD/Percepta prediction are available (WoE, Kr. 2).The prediction is considered of moderate reliability.
Additional information
ACD/Percepta predicted for ADPA an acute oral LD50 to rat equal to 750 mg/kg. The prediction is considered of moderate reliability (RI in range 0.5 - 0.75). ACD/Percepta predicted for ADPA an acute oral LD50 to mouse equal to 1000 mg/kg. The prediction is considered of moderate reliability. Based on these data, ADPA is considered as harmful if swallowed.
Justification for selection of acute toxicity – oral endpoint
The lowest LD50 predicted for ADPA was 750 mg/kg bw in rat.
Justification for classification or non-classification
ACD/Percepta predicted for ADPA an acute oral LD50 to mouse equal to 1000 mg/kg and an acute oral LD50 to rat equal to 750 mg/kg. Based on these data, ADPA is considered as harmful if swallowed and classified into Category. 4 (H302) according to CLP Regulation (1272/2008) criteria.
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