Registration Dossier
Registration Dossier
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EC number: 239-763-1 | CAS number: 15680-42-9
Nanomaterial Zeta potential
Administrative data
- Endpoint:
- nanomaterial Zeta potential
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
- Principles of method if other than guideline:
- Measurement by by Laser Doppler Electrophoresis using Zetasizer Nano (Malvern) and a folded capillary cell (DTS 1060; Malvern).
- GLP compliance:
- no
- Type of method:
- Laser-Doppler
- Details on methods and data evaluation:
- The samples were dispersed at room temperature in the background electrolyte solution (10 mmol/L KCl) and adjusted to the corresponding pH by 0.1M NaOH or HCl. The concentration of the samples was adjusted to the signal intensity in the range of 3000–7000 kcps. The results are the average of two measurements. The instrument was calibrated with Malvern Standard DTS 1235. We recorded the electrophoretic mobility across the titration range of pH 3–10 to identify the isoelectric point where the electrophoretic mobility crosses zero. Using the dispersed size determined by analytical ultracentrifugation (AUC), mobility, and pH 7.
Test material
- Reference substance name:
- [1-[[(2-hydroxyphenyl)imino]methyl]-2-naphtholato(2-)-N,O,O']copper
- EC Number:
- 239-763-1
- EC Name:
- [1-[[(2-hydroxyphenyl)imino]methyl]-2-naphtholato(2-)-N,O,O']copper
- Cas Number:
- 15680-42-9
- Molecular formula:
- C17H11CuNO2
- IUPAC Name:
- [1-[[(2-hydroxyphenyl)imino]methyl]-2-naphtholato(2-)-N,O,O']copper
- Test material form:
- solid: nanoform
- Details on test material:
- - Substance type: pigment
- Physical state: Solid / greenish yellow
- Name of test material (as cited in study report): Irgazin Yellow L 0800
- Lot/batch No.: 0005629903
- Analytical purity: 99.0 %
- Purity test date: 2013
- Expiration date of the lot/batch: unlimited stability under storage conditions
- Stability under test conditions: stable
- Storage condition of test material: room temperature
- Date of manufacture: 01 Dec 2011
Constituent 1
Data gathering
- Instruments:
- Zetasizer Nano (Malvern) and a folded capillary cell (DTS 1060; Malvern).
- Calibration:
- The instrument was calibrated with Malvern Standard DTS 1235.
- Reproducibility:
- no data
Results and discussion
Zeta potential
- Key result
- Zeta potential:
- -15 mV
- pH:
- 7
- Medium:
- 10 mmol/L KCl
- Remarks on result:
- other: average of 2 measurements
Applicant's summary and conclusion
- Conclusions:
- The test substance has a surface charge (Zeta potential) of -15 mV at pH 7.
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